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During the latter half of the 20th century, it was noticed that global amphibian populations had entered a state of unusually rapid decline. Hundreds of species have since become categorized as “missing” or “lost,” a growing number of which are now believed extinct. Amphibians are often regarded as environmental indicator species because of their highly permeable skin and biphasic life cycles, during which most species inhabit aquatic zones as larvae and as adults become semi or wholly terrestrial. This means their overall health is closely tied to that of the landscape.

On September 27, 1962, Rachel Carson published the book Silent Spring, which warned against the harmful effects of pesticides on the environment, especially on birds, without knowing that insects that are of vital importance for biodiversity and food would be central in it. Dutch toxicologist Henk Tennekes published in September 2010 a scientific article in a professional journal for toxicology, followed by the book "A Disaster in the Making" and describes the ecological disaster as follows: "The pesticides industry creates a 'toxic landscape' in which only the crop can survive."

Rachel Carson escribió el 27 de septiembre de 1962 Primavera Silenciosa, (Silent Spring) que advertía de los efectos perjudiciales de los pesticidas en el medio ambiente -especialmente en las aves- sin saber que los polinizadores vitales para la biodiversidad y la alimentación serían uno de los más perjudicados en su libro ya culpaba a la industria química de la creciente contaminación.​ En septiembre del 2010 el Dr Toxicólogo Henk Tennekes publicó un articulo científico en una revista de toxicología, Siguió un libro….. “Un Desastre en Potencia”.

In the summer of 2010, Henk Tennekes from Experimental Toxicology Services Nederland at Zutphen warned that the accumulation of neonicotinoids in the environment would not only decimate useful insects but also have a knock-on effect on other species, including birds (Curr. Biol. (2011) 21, R137–R139). At the time, Tennekes did not find much support for his views and went on to publish his warnings as a book — The Systemic Insecticides: A Disaster in the Making.

A 2015 study co-authored by Paul Ehrlich, professor emeritus of biology, and colleagues showed that Earth has entered an era of mass extinction unparalleled since the dinosaurs died out 66 million years ago. The specter of extinction hangs over about 41 percent of all amphibian species and 26 percent of all mammals, according to the International Union for Conservation of Nature (IUCN), which maintains a list of threatened and extinct species.

Mit rund 25'800 bedrohten Tier- und Pflanzenarten sei im zu Ende gehenden Jahr ein neuer dramatischer Höchststand erreicht worden. Ein Jahr zuvor waren es noch 24'000 bedrohte Arten. "Wir Menschen verursachen das grösste Artensterben seit Ende der Dinosaurier", resümierte Eberhard Brandes, Vorstand des WWF Deutschland. Auch in der Schweiz gingen die Bestände einiger Arten merklich zurück. Mehr als 40 Prozent der Insektenarten in der Schweiz gälten als bedroht, darunter Bienen und Schmetterlinge, sagte WWF-Sprecherin Perrette Rey in Lausanne auf Anfrage.

The 20th annual BirdTrends report highlights the rapid decline of the greenfinch, whose population has dropped by 59pc in the UK in just ten years. Bird experts say the decline is caused by a widespread and severe outbreak of a disease called trichomonosis, which first affected bird populations in 2006. The steepest long-term populations declines measured are for Turtle Dove, Tree Sparrow, Willow Tit, Grey Partridge and Nightingale, which have all declined by 90% or more since 1967, as, almost certainly, has Lesser Spotted Woodpecker.

The U.S. Environmental Protection Agency released multiple scientific assessments today that found commonly used neonicotinoid pesticides can kill and harm birds of all sizes. Separate analyses also found the pesticides pose significant danger to aquatic invertebrates, which play a crucial role in supporting larger ecosystems. The troubling assessments come on the heels of earlier EPA analyses and thousands of scientific studies that have identified substantial risks to pollinators and aquatic invertebrates from this class of pesticides.

Rivers in England are contaminated with powerful insecticides, new testing has revealed, increasing concerns over the impact of the toxic chemicals on fish and birds. Eight rivers in England are heavily contaminated with neonicotinoid pesticides. Two of the rivers, the Waveney on the border between Norfolk and Suffolk, and the Tame in the West Midlands, had an “acute level” of pollution, according to tests conducted by the Environment Agency last year.