The historic disaster in regulatory toxicology: the adoption of the ADI concept
Henk Tennekes refers to last century’s fifties, wherein the Germans Hermann Druckrey (1904-1994) and his friend, Chemistry Nobel laureate (1939) Adolf Butenand (1903-1995), advocated in the international community for a risk-prevention policy of dose-effect research for all pesticides. They wanted to prevent irreversible effects of pesticides. On the other hand there was the French René Truhaut, who advocated for the acceptable daily intake as the risk-management strategy for pesticide allowance for practical use.